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Pure Myristoyl Hexapeptide-23 Advanced Skin Tightening

Products Name Myristoyl Hexapeptide-23
INCI Name Myristoyl Hexapeptide-23
Specification  ≥98% (HPLC)
Molecular Weight ~811.9 g/mol
Chemical Formula C₄₁H₇₀N₁₀O₉
Appearance White to off-white lyophilized (freeze-dried) powder.
Solubility Soluble in water.
    Silk-peptide-(29)
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    Product Description

    1. Mechanism of Action (MOA)
    Myristoyl Hexapeptide-23 is a biomimetic lipopeptide engineered to target skin sagging and loss of elasticity through dual mechanisms of action:
    Tensin-Like Cytoskeletal Regulation
    Mimics the N-terminal sequence of tensin protein
    Modulates actin polymerization in dermal fibroblasts
    Reduces excessive stress fiber formation induced by aging and UV exposure
    Extracellular Matrix (ECM) Reinforcement
    Promotes synthesis of key structural proteins including:
    Collagen I, III, and IV
    Fibronectin
    Laminin
    Strengthens dermal-epidermal junction (DEJ) architecture

    2.  In Vitro Efficacy Data
    Fibroblast Function Analysis
    68% reduction in actin stress fiber density in aged fibroblasts
    142% increase in collagen I synthesis vs. untreated controls
    98% enhancement in fibronectin production

    DEJ Component Studies
    156% upregulation of laminin-332 expression
    127% increase in collagen IV deposition
    Significant improvement in keratinocyte-fibroblast communication

    3. Clinical Results
    28-56 day clinical studies demonstrate:

    Skin Firmness & Elasticity
    21.3% improvement in cutometer measurements (R2 parameter)
    18.7% enhancement in skin elasticity (R5 parameter)
    89% of subjects showed visible improvement in jawline definition

    Wrinkle Reduction & Skin Quality
    31% reduction in deep wrinkle volume (3D image analysis)
    27% improvement in skin smoothness
    94% subject satisfaction with lifting effect

    Safety & Compatibility

    Thickeners

    Safety Profile

    *Non-irritating (HRIPT confirmed) *Non-sensitizing at recommended concentrations *Suitable for sensitive skin types
    Actives

    Formulation Compatibility

    *pH stability range: 4.5-7.2 *Compatible with common cosmetic ingredients: Hyaluronic acid and derivatives Other structural peptides Niacinamide Vitamin C derivatives Most botanical extracts
    Silk-peptide-(29)
    01

    Recommended Usage & Formulations

    Optimal Concentration: 3-5%

    Preferred Formulations
    Lifting and firming serums
    Neck and décolletage creams
    Facial contouring treatments
    Age-delay concentrated ampoules
    O/W emulsions for mature skin

    Application Frequency
    Twice daily for optimal results
    Suitable for long-term use

     Summary & Key Selling Points

    Applications1
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    Dual-Action Technology

    *Addresses both cytoskeletal tension and ECM quality *Provides immediate and long-term benefits
    Applications3
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    Clinically Verified Efficacy

    *Significant improvement in skin firmness and elasticity *Visible reduction in sagging and wrinkle depth
    Applications5
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    Superior Safety Profile

    *Well-tolerated across all skin types *Excellent formulation flexibility
    Applications5
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    Market Differentiation

    *Advanced biomimetic approach to skin lifting *Scientifically proven mechanism of action *Ideal for premium anti-aging positioning
    storage

    Storage

    Store in a closed container at a dry place at room temperature.

    gmo1

    Animal Testing

    Not animal tested

    vegetarian1

    Vegan

    Does not contain animal-derived components

    gmo

    GMO

    No data available

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